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  • Immunity

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    Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut

    Duan J, Matute JD, Unger LW, Hanley T, Schnell A, Lin X, Krupka N, Griebel P, Lambden C, Sit B, Grootjans J, Pyzik M, Sommer F, Kaiser S, Falk-Paulsen M, Grasberger H, Kao JY, Fuhrer T, Li H, Paik D, Lee Y, Refetoff S, Glickman JN, Paton AW, Bry L, Paton JC, Sauer U, Macpherson AJ, Rosenstiel P, Kuchroo VK, Waldor MK, Huh JR, Kaser A, Blumberg RS

    DOI:

    https://doi.org/10.1016/j.immuni.2023.02.018

  • Angewandte Chemie International Edition

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    Digital Microfluidics and Magnetic Bead-Based Intact Proteoform Elution for Quantitative Top-down Nanoproteomics of Single C. elegans Nematodes

    Leipert J, Kaulich PT, Steinbach MK, Steer B, Winkels K, Blurton C, Leippe M, Tholey A

    DOI:

    https://doi.org/10.1002/anie.202301969

  • The EMBO Journal

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    DNA sensing via the cGAS/STING pathway activates the immunoproteasome and adaptive T‐cell immunity

    Wang X, Zhang H, Wang Y, Bramasole L, Guo K, Mourtada F, Meul T, Hu Q, Viteri V, Kammerl I, Konigshoff M, Lehmann M, Magg T, Hauck F, Fernandez IE, Meiners S

    DOI:

    https://doi.org/10.15252/embj.2022110597

  • iScience

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    Proteoforms expand the world of microproteins and short open reading frame-encoded peptides

    Cassidy L, Kaulich PT, Tholey A

    DOI:

    https://doi.org/10.1016/j.isci.2023.106069

  • Gut Microbes

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    Pathometagenomics reveals susceptibility to intestinal infection by Morganella to be mediated by the blood group-related B4galnt2 gene in wild mice

    Vallier M, Suwandi A, Ehrhardt K, Belheouane M, Berry D, Čepić A, Galeev A, Johnsen JM, Grassl GA, Baines JF.

    DOI:

    https://doi.org/10.1080/19490976.2022.2164448

  • Nature

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    MYC multimers shield stalled replication forks from RNA polymerase

    Solvie D, Baluapuri A, Uhl L, Fleischhauer D, Endres T, Papadopoulos D, Aziba A, Gaballa A, Mikicic I, Isaakova E, Giansanti C, Jansen J, Jungblut M, Klein T, Schülein-Völk C, Maric H, Doose S, Sauer M, Beli P, Rosenwald A, Dobbelstein M, Wolf E*, Eilers M*

    DOI:

    https://doi.org/10.1038/s41586-022-05469-4

  • Archives of Microbiology

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    Bacteroides muris sp. nov. isolated from the cecum of wild-derived house mice

    Fokt H, Unni R, Repnik U, Schmitz RA, Bramkamp M, Baines JF, Unterweger D

    DOI:

    https://doi.org/10.1007/s00203-022-03148-6

  • Science

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    A conserved Bacteroidetes antigen induces anti-inflammatory intestinal T lymphocytes

    Bousbaine D, Fisch LI, London M, Bhagchandani P, Rezende de Castro TB, Mimee M, Olesen S, Reis BS, VanInsberghe D, Bortolatto J, Poyet M, Cheloha RW, Sidney J, Ling J, Gupta A, Lu TK, Sette A, Alm EJ, Moon JJ, Victora GD, Mucida D, Ploegh HL, Bilate AM

    DOI:

    https://doi.org/10.1126/science.abg5645

  • Immun Inflamm Dis

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    Oral application of vancomycin alters murine lung microbiome and pulmonary immune responses

    S. Pfeiffer, G. Jatzlauk, J.V. Lund, E. Boateng E, D. Kovacevic, M. Hylkema, S. Bartel, M. Schloter, S. Krauss-Etschmann (corresponding author)

  • aLife

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    Key features of the genetic architecture and evolution of host-microbe interactions revealed by high-resolution genetic mapping of the mucosa-associated gut microbiome in hybrid mice

    Doms S, Fokt H, Rühlemann MC, Chung CJ, Kuenstner A, Ibrahim SM, Franke A, Turner LM, Baines JF

    DOI:

    https://doi.org/10.7554/eLife.75419