Hyperbaric Oxygenation Therapy (HBOT)
Coming historically from Diving Medicine, HBOT has nowadays developed towards a multidisciplinary therapeutic option in a number of medical fields, where the application of hyperbaric pure oxygen causes positive clinical effects, because of the physical and/or biochemical properties of extreme high tissue pO2.
Since the complex effects of hyperbaric hyperoxia are currently not fully understood, there is need for basic as well as clinical research in this field.
Research Description
The Section for Maritime Medicine currently focuses primarily on research in basic cellular and inflammation-modulating effects of hyperbaric oxygenation, special aspects in diving physiology, and questions in sea sickness:
Our work focuses on translational research and contributes to the expansion of the clinical use of hyperbaric oxygen therapy (HBOT) beyond diving accidents and carbon monoxide intoxication. The immunological response to HBOT, which leads to immunomodulatory effects on the T- and B-cell compartments, is of particular interest.
Project leader
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Prof. Dr. Andreas Koch
Principal Investigator+49 (0)431 5409 1418
Team
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Sebastian Klapa
Post-Doc+49 (0) 431 5409 1503
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Wataru Kähler
Post-Doc+49 (0)431 5409 1515
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Julia Böge
Lab technician+49 (0)431 5409 1622
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Gordon Vollert
PhD-student -

Bente Rieger
PhD-student+49 (0)431 5409 1756
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Rieke Scharbrodt
PhD-student -

Nora Speetzen
Assistance+49 (0)431 5409 1460
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Handan Müftüoglu
Assistance
Publications
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Annals of the Rheumatic Diseases
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Decreased endothelin receptor A autoantibody levels are associated with early ischaemic events in patients with giant-cell arteritis.
Klapa S, Müller A, Koch A, Heidecke H, Kähler W, Junker J, Schinke S, Riemekasten G, Lamprecht P
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Free Radical Research
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Effect of hyperoxia on the immune status of oxygen divers and endurance athletes
Tillmans F, Sharghi R, Noy T, Kähler W, Klapa S, Sartisohn S, Sebens S, Koch A
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PraxisMagazin
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Tanzen – ein gesunder Präventionssport
Koch A, Kähler W, Klapa S
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PraxisMagazin
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See- und Reisekrankheit – Altbekannt und doch immer noch aktuell.
Koch A, Sartisohn S, Grams B, Kähler W, Klapa S
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DruckPunkt
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Tauchen und Hypertonie
Koch A, Weisser B
